Kikuchi-Fujimoto Disease: A Rare Presentation with Localized Iliac Lymphadenitis

Authors

  • Anil Arora Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi
  • Ashish Kumar Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi
  • Naresh Bansal Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi
  • Praveen Sharma Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi
  • Vikas Singla Department of Gastroenterology, Sir Ganga Ram Hospital, New Delhi
Abstract:

Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease characterized by histiocytic necrotising lymphadenitis. Though several viral agents or an autoimmune etiology has been proposed as causative, the exact cause remains unknown. It has a female predilection and most commonly seen among young Asian people. Patients usually present with a febrile illness and the presence of lymphadenopathy may provide a clue to diagnosis. The most common site of lymphadenopathy is cervical lymph nodes while intra-abdominal involvement is uncommon. Cases of KFD presenting with intra-abdominal lymphadenopathy have been reported to occur with equal frequency in both sexes. Abdominal tuberculosis, non-Hodgkin’s lymphoma, and systemic lupus erythematosus are close differential diagnoses for this type of presentation. Treatment is mostly supportive as the disease usually resolves spontaneously; steroids are only required in severe cases. We report a 32-year-old male patient of intra-abdominal lymphadenitis that presented as fever of unknown origin (FUO) and diagnosed by excisional biopsy as a case of KFD.

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Journal title

volume 42  issue 1

pages  94- 97

publication date 2016-11-19

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